Thursday, October 13, 2016

Ingredients for a Fracture-Free Life

Health News
By VRP Staff
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When it comes to the health of your bones, you don’t really appreciate what you’ve got until it’s gone. Your skeleton serves as the frame upon which your entire body is built, so it’s no surprise that the erosion of your bones comes with very serious consequences.
Osteoporosis is a slow, silent and usually symptomless condition marked by gradual bone mass reduction, which ultimately leads to a significantly increased risk of vertebral and hip fractures—a leading cause of death, disability and impaired quality of life in the elderly population.1-6 Among these osteoporotic fractures, vertebral fractures are the most common and devastating, with studies showing that—among subjects between the ages of 64 and 82 years old—vertebral fractures occur with more severe osteoporosis, result in a greater impact on quality of life and are associated with a dramatically poorer prognosis than hip fractures.7
You may think that this is primarily a female concern—but, in fact, statistics reveal that as many as two million men in the US struggle with osteoporosis, resulting primarily from low levels of vitamin D and dangerous declines in testosterone.8-9 What’s worse, emerging research indicates that the bisphosphonate compounds commonly used to treat bone loss may actually have a negative effect on bone health with prolonged use.10-11
So, what can you do to ensure that your bones stay dense and strong? Luckily, just a few key nutrients can stave off the telltale signs of osteoporosis—reducing your risk of fractures and disability as you age.
An analysis of 29 randomized trials showed, for example, that supplementation with a combination of calcium and vitamin D3 is able to reduce fracture risk by 24 percent, while curbing bone loss as well.12 High doses of a quality vitamin K supplement (such as Ultra K2, from Vitamin Research Products) also appear to increase bone strength, reducing clinical fracture incidence in postmenopausal women with a history of repeated vertebral fractures.13
Ipriflavone, another critical bone-building substance (found in Osteoflavone Complex from VRP), suppresses bone breakdown. Large, double-blind trials have shown that with daily use, ipriflavone delivers significant boosts in total-body bone mineral density.14-15 A combination of all of these natural, side-effect-free nutrients—paired with the clinically proven bone-building mineral strontium, also available now from VRP—will help ensure that your bones stay strong at any age…supporting you so you can live an independent, active lifestyle through your 60s, 70s and beyond.16
References:
1. Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis International. 2006;V17:1726-1733.
2. Hasserius R, Karlsson MK, Jonsson B, Redlund-Johnell I, Johnell O. Long-term morbidity and mortality after a clinically diagnosed vertebral fracture in the elderly—a 12- and 22-year follow-up of 257 patients. Calcif Tissue Int. 2005;76:235-242.
3. Caliri A, De Filippis L, Bagnato GL, Bagnato GF. Osteoporotic fractures: mortality and quality of life. Panminerva Med. 2007;49:21-27.
4. Lips P, van Schoor NM. Quality of life in patients with osteoporosis. Osteoporosis International. 2005;16:447–455. doi: 10.1007/s00198-004-1762-7.
5. Ettinger B, Black DM, Nevitt MC, Rundle AC, Cauley JA, Cummings SR, Genant HK. Contribution of vertebral deformities to chronic back pain and disability. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res. 1992;7:449-456.
6. Nevitt MC, Ettinger B, Black DM, Stone K, Jamal SA, Ensrud K, Segal M, Genant HK, Cummings SR. The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med. 1998;128:793-800.
7. Hallberg I, Bachrach-Lindström M, Hammerby S, Toss G, Anna-Christina E. Health-related quality of life after vertebral or hip fracture: a seven-year follow-up study. BMC Musculoskelet Disord. November 3, 2009; 10: 135. Published online ahead of print.
8. National Osteoporosis Foundation website, www.nof.org, accessed on June 10, 2010.
9. Ducharme N. Clin Geriatr Med. 2010 May;26(2):301-9. Male osteoporosis. Ducharme N.
10. Somford MP, Geurts GF, den Teuling JW, Thomassen BJ, Draijer WF. Long-Term Alendronate Use Not without Consequences? Int J Rheumatol. Published online Jan 27, 2010.
11. Ing-Lorenzini K, Desmeules J, Plachta O, Suva D, Dayer P, Peter R. Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital. Drug Saf. 2009;32(9):775-85.
12. Stránský M, Rysavá L. Nutrition as prevention and treatment of osteoporosis. Physiol Res. 2009;58 Suppl 1:S7-S11.
13. Iwamoto J. [Anti-fracture efficacy of vitamin K] [Article in Japanese]. Clin Calcium. 2009 Dec;19(12):1805-14.
14. Miyauchi A, et al. Novel ipriflavone receptors coupled to calcium influx regulate osteoclast differentiation and function. Endocrinology. 1996; 13: 3544-50.
15. Agnusdei D, Bufalino L. Efficacy of ipriflavone in established osteoporosis and long-term safety. Calcif Tissue Int. 1997;61 Suppl 1:S23-7.
16. Marie PJ, Skoryna SC, Pivon RJ, Chabot G, Glorieux FH, Stara JF. Histomorphometry of bone changes in stable strontium therapy. In: Trace substances in environmental health XIX, edited by D.D. Hemphill, University of Missouri, Columbia, Missouri, 1985, 193-208.

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